HPP: A Journey Through the Body

Learn how this metabolic bone disorder impacts the body.

HPP in Toddlers HPP in Adults

2017 Research Grant Applications Due April 15th

For information regarding applying for a 2017 Research Grant, please visit our news post.

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Educate. Empower. Connect.

Soft Bones Foundation was formed in 2009 to provide information and a community to educate, empower and connect patients living with hypophosphatasia (HPP), their families and caregivers.

The mission of Soft Bones, Inc. is to provide valuable information, education and support for people living with hypophosphatasia (HPP), their families and caregivers. The Foundation promotes research of this rare bone disease through awareness and fund-raising efforts.

What Is HPP?

HPP is a condition that affects healthy development of bones and teeth, making bones softer and more likely to fracture. People who have HPP have trouble making an enzyme called alkaline phosphatase, or ALP. Without this important ALP enzyme, certain chemicals build-up and prevent calcium and phosphorus from binding together and depositing in the bones. As a result, bones can become soft, curved and fragile, and teeth may become loose or fall out prematurely.

For more information, continue reading What Is HPP.